Transient and mild GI effects were the most commonly reported side effects in fenugreek groups; however, comparisons could not be drawn with hypoglycemic agents due to a lack of data on the latter. Fenugreek has been used to stimulate milk production in breast-feeding mothers, but data are insufficient to determine its efficacy and safety, and the extent of transmission of fenugreek-derived constituents into breast milk is unknown. Can fenugreek increase breast size? The name of the genus, Trigonella, derives from the Latin for "little triangle", in reference to the shape of fenugreek yellowish-white flowers. Bleeding may occur. Only 1 study out of 7 showed an effect on insulin.44 Study methodology limitations exist. Reductions of serum cholesterol (15% to 33%) from baseline were reported in all the trials identified.47 Results from further studies conducted among patients with diabetes found equivocal results, with most reporting decreases in total cholesterol, triglycerides, and low-density lipoprotein.8, 34, 89, Antifungal and antibacterial properties have been demonstrated.17 A French patent was granted to a product containing extracts of several herbal products, including fenugreek, purported to have activity against human and animal flagellate parasites.48, Oral administration of fenugreek seed fractions and fiber products resulted in dose-dependent gastric protection similar to that of nonprescription antacid medication.17, 49, 50, 77 Because of the association of Helicobacter pylori with gastritis, peptic ulcer, and gastric cancer, in vitro experimentation was conducted in H. pylori-infected gastric epithelial cells with 24 medicinal plants indigenous to Pakistan to evaluate their effect on secretion of IL-8 and generation of reactive oxygen species (ROS) in order to assess anti-inflammatory and cytoprotective effects. turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. The seeds are rich in protein, and the plant is grown as animal forage. Fenugreek or most commonly ‘methi‘ in Hindi is a popular spice having a strong scent and a pungent flavor. It develops over time, according to use, look, and lore. Scientific name is the name conforming to the International Code of Nomenclature for algae, fungi, and plants (ICN). It was a key ingredient in a 19th century patent medicine Lydia Pinkham's Vegetable Compound, which was used for dysmenorrhea and postmenopausal symptoms. Outcome measures included the Unified Parkinson's Disease Rating Scale (UPDRS), and Hoehm and Yahr (H & Y) staging measured at baseline and at 6 months. The mucilages of fenugreek's and several other plants' seeds have been determined and their hydrolysates analyzed.11 Fenugreek gel consists chiefly of galactomannans, characterized by their high water-holding capacity. Fenugreek has very few problems in an organic garden. Common name of Fenugreek is the name which changes with change in the regions. So what is Fenugreek powder? Fenugreek goes by many names around the world. This product may be unsafe when used before surgery or other medical procedures. The plant thrives in full sun and in rich, well-drained soils, and has a spicy odor that remains on the hands after contact.1, 2, Fenugreek herb has been used for centuries as a cooking spice in Europe and remains a popular ingredient in pickles, curry powders, and spice mixtures in India and other parts of Asia. it helps a lot. Liver transplant was also more frequent with toxicity from non-bodybuilding supplements (13%) than with conventional medications (3%) (P<0.001). Maple syrup urine disease, a disorder of branched-chain amino acid catabolism that results in abnormal accumulations of amino acids and their metabolites, was suspected in a healthy infant born to a mother who ingested a paste prepared from fenugreek seeds early in labor.53 Fenugreek, maple syrup, and the urine of patients with the disease share a characteristic odor originating from the common constituent sotolone. Fenugreek seeds have been used in traditional medicine to augment breast milk supply.54, 92 Fenugreek has been shown to stimulate sweat production, offering a possible mechanism of action. The slightly bitter, spicy taste to the leaves tends to deter varmints and deer. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Low to moderate doses have been shown to produce mild CNS stimulation in rats with higher doses producing twitches, tremors, painful stimuli, and generalized convulsions.90, Data collected between 2004 and 2013 among 8 US centers in the Drug-induced Liver Injury Network revealed 15.5% (130) of hepatotoxicity cases was caused by herbals and dietary supplements whereas 85% (709) were related to medications. Fenugreek extracts are also used in soaps and cosmetics. Fenugreek in Spanish can be different from Fenugreek in English. A standardized hydroalcoholic extract of fenugreek seeds is available, and a trial evaluated its use in patients with Parkinson disease at 300 mg twice daily for a period of 6 months. Overall, the number of severe liver injury cases was significantly higher from supplements than conventional medications (P=0.02). When ingested in culinary quantities, fenugreek is usually devoid of adverse reactions. Much research on fenugreek has been conducted in India and other countries, focusing on its potential for the treatment of diabetes. Other names for the herbal spice include Greek hay, Greek hay seed, bird’s foot, Greek clover, foenugreek, sicklefruit fenugreek, hu lu ba, alholva, … Common Name of Fenugreek in other languages is an interesting information one should know. It is cultivated and used all around the world, but mainly in India. The availability of only 1 study for pre-diabetes limited the usefulness of disease subgroup analysis. Fenugreek is a plant also known as Alholva, Bird's Foot, Bockshornklee, Bockshornsame, Chandrika, Fenogreco, Foenugraeci Semen, Greek Clover, Greek Hay, Greek Hay Seed, Hu Lu Ba, Medhika, Methi, Sénégrain, Trigonella, Woo Lu Bar, and other names. [Source 47)] Fenugreek seeds. The remaining residue is rich in nitrogen and potassium, and is used as an agricultural fertilizer.2, 3, The leaves contain at least 7 saponins, known as graecunins, which are glycosides of diosgenin. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Studies in patients with type 2 diabetes and hypercholesterolemia have used 5 g/day of seeds or 1 g/day of a hydroalcoholic extract of fenugreek.34, A trial in patients with Parkinson disease evaluated the safety of a standardized hydroalcoholic extract of fenugreek seeds at a dosage of 300 mg twice daily over 6 months.33, Fenugreek seed powder 1.8 to 2.7 g taken 3 times daily for the first 3 days of menstruation was used in primary dysmenorrhea (total daily dose, 5.4 to 8.1 g).84, Avoid use in pregnancy. 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